职 称: | 研究员 |
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学 历: | 博士研究生 |
联系方式: | 86-27-68780160 |
电子邮件: | danxianghan#ihb.ac.cn(请改#为@) |
办 公 室: | |
个人网页: |
简历介绍:
教育经历
1997-2001 武汉大学 药学专业 理学学士
2001-2006 中国科学院水生生物研究所 水生生物学 理学博士
研究经历
2006-2010 博士后研究员, 美国亚利桑那州立大学
2010-2014 助理研究教授, 美国亚利桑那州立大学
2014-Now 研究员, 中国科学院水生生物研究所
研究方向:
藻类生物学与藻类生物技术。研究内容涉及藻类生理生化及分子细胞生物学,主要包括1)油脂生物合成、调控及储存机制,2)类胡萝卜素等高附加值产品的生物合成,3)微藻抗逆生物学,4)微藻系统代谢工程及合成生物学。
代表论著:
Guanqun Chen, Baobei Wang, Danxiang Han, Milton Sommerfeld, Yinghua Lu, Feng Chen andQiang Hu (2015) Molecular mechanisms of the coordination between astaxanthin and fatty acid biosynthesis in Haematococcus pluvialis (Chlorophyceae). The Plant Journal 81, 95-107
Baobei Wang, Zhen Zhang, Qiang Hu, Milton Sommerfeld, Yinghua Lu and Danxiang Han (2014) Cellular capacities for high-light acclimation developed in life cycle of the green alga Haematococcuspluvialis. PLoS One DOI: 10.1371/journal.pone.0106679
Yunho Gwak, Yong-sic Hwang, Baobei Wang, Minju Kim, JooyeonJeong, Choul-Gyun Lee, Qiang Hu, Danxiang Han & EonSeonJin (2014) Comparative analyses of lipidomes and transcriptomes reveals a concerted action of multiple defensive systems against photooxidative stress in Haematococcus pluvialis. Journal of Experimental Botany 65: 4317-4334 (Co-Corresponding Author)
Li, J., Han, D., Wang D., Ning, K., Jia, J., et al (2013) Choreography of transcriptomes and lipidomes of Nannochloropsis reveals the mechanisms of oleaginousness in microalgae. Plant Cell26: 1645-1665 (Co-First Author)
Wang, D., Ning, K., Li, J., Han, D., Wang H., et al (2014) Nannochloropsis phylogenome revealed evolution of microalgal oleaginous traits. Plos Genetics 10: e1004094
Han, D., Li, Y. & Hu, Q. (2013) Biology and commercial aspects of Haematococcus pluvialis. pp. 388-405. In: Richmond, A. & Hu, Q. (eds.): Handbook of Microalgal Culture, 2nd edition, Wiley-Blackwell, West Sussex, UK.
Han, D., Deng, Z., Lu, F. & Hu, Z. (2013) Biology and biotechnology of edible Nostoc, pp. 433-444.In: Richmond, A. & Hu, Q. (eds.): Handbook of Microalgal Culture, 2nd edition, Wiley-Blackwell, West Sussex, UK.
Li, Y., Chen, W., Shen, H., Han, D., Li, Y., Jones, H., Timlin JA.& Hu, Q. (2013) Basic culturing and analytical measurement techniques, pp.37-68. In: Richmond, A. & Hu, Q. (eds.): Handbook of Microalgal Culture, 2nd edition, Blackwell Science Ltd., Oxford, UK.
Li, Y., Han, D., Yoon, K., Zhu, S., Sommerfeld, M. & Hu, Q. (2013) Molecular and cellular mechanisms for lipid synthesis and accumulation in microalgae: biotechnological implication, pp. 545-565.In: Richmond, A. & Hu, Q. (eds.): Handbook of Microalgal Culture, 2nd edition, Wiley-Blackwell, West Sussex, UK.
Han, D., Li, Y. & Hu, Q. (2013) Astaxanthin in microalgae: Biosynthesis pathways, regulation and biotechnological applications. Algae 28: 131-147
Yoon, K.S., Han, D., Li, Y. Sommerfeld, M. & Hu Q. (2012) Phospholipid:diacylglycerolacyltransferase is a multifunctional enzyme involved in membrane lipid turnover and degradation while synthesizing triacylglycerol in the unicellular green microalga Chlamydomonasreinhardtii. Plant Cell 24: 3708-24 (Co-First Author)
Wang, J., Han, D., Sommerfeld, M. & Hu, Q. (2012) Effect of initial biomass density on growth and astaxanthin production of Haematococcuspluvialis in an outdoor photobioreactor.Journal of Applied Phycology DOI: 10.1007/S10811-012-9859-4
Han, D., Wang, J., Sommerfeld, M. & Hu, Q. (2012) Susceptibility and protective mechanisms of motile and non-motile cells of Haematococcuspluvialis (Chlorophyceae) to photooxidative stress.Journal of Phycology 48:693-705
Collins, A., Jones, H., Han, D., Hu, Beechem, T. &Timlin, J. (2011) Carotenoid distribution in living cells of Haematococcuspluvialis (Chlorophyceae).Plos ONE 6: e24302 DOI: 10.1371/journal.pone.0024302
Li, Y., Han, D., Sommerfeld, M. & Hu, Q. (2011) Photosynthetic carbon partitioning and lipid production in the oleaginous microalga Pseudochlorococcum sp. (Chlorophyceae) under nitrogen-limited conditions.Bioresource Technology 102: 123-9
Li, Y., Han, D., Hu, G., Sommerfeld, M. & Hu, Q. (2010) Inhibition of starch synthesis results in overproduction of lipids in starchless mutants of Chlamydomonasreinhardtii.Biotechnology & Bioengineering, 107: 258-68
Li, Y., Han, D., Hu, G., Dauville, D., Sommerfeld, M., Ball, S. & Hu, Q (2009) Chlamydomonasstarchless mutant defective in ADP-glucose pyrophosphorylase hyper-accumulates triacylglycerol. Metabolic Engineering 12: 387-91
Han, D., Fan, Y. & Hu, Z. (2009) An evaluation of four phylogenetic markers in Nostoc: Implications for cyanobacterial phylogenetic studies at the intrageneric level. Current Microbiology 58: 170-176