阐明了MARCKS家族蛋白通过介导重要信号因子骨形成蛋白（BMP）的转运分泌从而调控BMP信号通路的分子机制；创建了全时相、无间断特异标记鲤生殖细胞谱系的策略，揭示了原始生殖细胞数目对性腺分化的影响；以斑马鱼为模型，研究并阐明了鱼类雄激素11-KT在性腺分化、第二性征发育及生殖行为方面的作用，发现了肾上腺素Cortisol促进斑马鱼卵子成熟的功能。

代表性论文：

1.      Qifeng Zhang#, Ding Ye#, et al., Zebrafish cyp11c1 Knockout Reveals the Roles of 11-ketotestosterone and Cortisol in Sexual Development and Reproduction, Endocrinology, Volume 161, Issue 6, June 2020, bqaa048

2.      Ding Ye#, Xiaosi Wang#, et al., Marcksb plays a key role in the secretory pathway of zebrafish Bmp2b. PLoS Genet. 2019 Sep 23;15(9):e1008306.

3.      Ding Ye, Lin Zhu, et al., Abundance of Early Embryonic Primordial Germ Cells Promotes Zebrafish Female Differentiation as Revealed by Lifetime Labeling of Germline. Mar Biotechnol (NY). 2019 Apr;21(2):217-228.

4.      Ding Ye#, Huaping Xie#, et al., Endoderm convergence controls subduction of the myocardial precursors during heart-tube formation. Development. 2015, 142(17): 2928-2940.

5.      Ding Ye, Zuoyan Zhu, Yonghua Sun. 2015. Fish genome manipulation and directional breeding. Sci China Life Sci 58, 170-177.

6.      Ding Ye, Fang Lin*. S1pr2/Gα13 signaling controls myocardial migration by regulating endoderm convergence. Development. 2013 140(4):789-99.

7.      Ding Ye, QW Yang, et al., Gα13 is closely related to hematopoiesis in zebrafish. Mol Biol Rep. 2011.38(4):2685-94

8.      Ding Ye, D Lv, et al., Cloning and characterization of a rice field eel vasa-like gene cDNA and its expression in gonads during natural sex transformation. Biochemical Genetics, 2007, 45: 211-224.

专利：

熊凤，孙永华，叶鼎，朱作言。一种用于原始生殖细胞靶向突变的转基因载体及制备方法和用途。中国发明专利，专利号：ZL 2015 1 0809203.X