![]() 个人简历: 男,博士,研究员。 1988~1992 武汉大学生物学系微生物学专业,获理学学士学位 1992~1997 中国科学院水生生物研究所水生生物学专业,师从王伟俊研究员和沈韫芬院士,获理学博士学位 1997~2000 南京农业大学动物医学院博士后,从事水生生物病原研究 2000~2003 剑桥大学通信系统研究中心、遗传学系,Bioinformatics Research Associate 2004~2009 美国加州 Sidney Kimmel Cancer Center, Senior Research Scientist, Director of Lechner-Haag Genomics Core 2009~2011 美国加州圣迭戈疫苗研究所,Bioinformatics Director 2010~2011 美国加州大学尔湾分校病理学与检验医学系,Assistant Project Scientist Step II 2011~ 中国科学院水生生物研究所“百人计划”入选者,水体生物信息分析学科组组长,研究员。 研究方向: 基因组学与生物信息学。通过高通量的二代测序数据和基因芯片数据来进行基因组学与生物信息学方面的研究。研究内容包括: 生物标记 基因组组装与注解 比较基因组学及算法研究 数据库与软件平台开发 专家类别:百人 获奖及荣誉: 代表论著: [1] Jia, Z., Wang, Y., Sawyers, A., Yao, H., Rahmatpanah, F., Xia, X.-Q., Xu, Q., Pio, R., Turan, T., Koziol, J., Goodison, S., Carpenter, P., Wang-Rodriguez, J., Simoneau, A., Meyskens, F., Sutton, M., Lernhardt, W., Beach, T., McClelland, M. & Mercola, D., Diagnosis of prostate cancer using differentially expressed genes in stroma. Cancer Research, 2011, 71(14):2476-2487. [2] Xia, X.-Q., McClelland, M., Wang, Y., TabSQL - a MySQL tools to facilitate data queries with public databases. BMC Bioinformatics, 2010, 11: 342. [3] Wang, Y., Xia, X.-Q., Jia, Z., Sawyers, A., Yao, H., Wang-Rodriquez, J., Mercola, D. & McClelland, M., In silico estimates of tissue components in surgical samples based on expression profiling data. Cancer Research, 2010, 70(16): 6448-6455. [4] Xia, X.-Q., McClelland, M., Wang, Y., PypeR, a Python package for using R in Python. Journal of Statistical Software, 2010, 35(Code Snippets 2): 1-8. [5] Kucerova, E., Clifton, S. W., Xia, X.-Q., Long, F., Porwollik, S., Fulton, L., Fronick, C., Minx, P., Kyung, K., Warren, W., Fulton, R., Feng, D., Wollam, A., Shah, N., Bhonagiri, V., Nash, W. E., Hallsworth-Pepin, K., Wilson, R. K., McClelland, M.& Forsythe, S. J., Genome sequence of Cronobacter sakazakii BAA-894 and Comparative Genomic Hybridization Analysis with Other Cronobacter Species. PLOS ONE, 2010, 5(3):e9556. [6] Xia, X.-Q., Jia, Z., Porwollik, S., Long, F., Hömme, C., Ye, K., Müller-Tidow, C., McClelland, M. & Wang, Y., Evaluating Oligonucleotide Probe Properties for DNA Microarray Probe Design. Nucleic Acid Research, 2010, 38(11): e121. doi: 10.1093/nar/gkq039. [7] Xia, X.-Q., McClelland, M., Porwollik, S., Song, W., Cong, X. & Wang, Y., WebArrayDB: cross-platform microarray data analysis and public data repository. Bioinformatics, 2009, 25(18): 2425 – 2429. [8] Wang, Y., McClelland, M. & Xia, X.-Q., Analyzing microarray data using WebArray. Cold Spring Harbor Protocols, 2009, 4(8), doi:10.1101/pdb.prot5260. [9] Tang, Y., Akbulut, H., Maynard, J., Petersen, L., Fang, X., Zhang, W.-W., Xia, X.-Q., Koziol J., Linton P.-J., and Deisseroth A., Vector Prime/Protein Boost Vaccine That Overcomes Defects Acquired during Aging and Cancer. Journal of Immunology, 2006, 177: 5697 - 5707. [10] Xia, X.-Q., McClelland, M. Wang, Y., WebArray: an online platform for microarray data analysis. BMC Bioinformatics, 2005, 6(1): 306. [11] Xia, X.-Q. & Wise, M. DiMSim: a discrete-event simulator of metabolic networks. Journal of Chemical Information and Computer Science, 2003, 43:1011-1019. |