 汪亚平 专家简介： 1963年9月出生，博士，中国科学院水生生物研究所研究员，博士生导师。1985年毕业于武汉大学生物系遗传学专业，1988年和2000年在中国科学院获理学硕士和博士学位。1988年至今，在中国科学院水生生物研究所工作，主要从事鱼类基因工程和功能基因组学研究，致力于鱼类重要经济性状相关基因的功能研究和分子育种实践。2002年获第四届“武汉优秀青年科技创新奖”，2004年获国务院特贡专家津贴。现任中国科学院水生生物研究所淡水生态与生物技术国家重点实验室副主任。 研究方向与主持课题： 研究方向: 鱼类功能基因组学及鱼类基因工程 实验室以中国重要的淡水养殖品种—草鱼(Ctenopharyngodon idellus)为主要研究对象，致力于发掘鱼类重要经济性状相关基因，包括快速生长、高效饵料利用、抗病抗逆和性别决定相关基因，解析基因的网络调控机制，揭示基因功能，并应用于鱼类分子育种实践。 主持课题： “草鱼出血病抗性相关基因的功能研究”(重点基金) “草鱼重要经济性状相关基因的克隆和功能研究”(863课题) “草鱼抗出血病品种的分子模块设计与培育”(先导专项A) “草鱼全基因组测序及框架图组装”(自主项目) 近五年发表研究论文： 1. Lian H, Hu W, Huang R, Du FK, Liao LJ, Zhu ZY, Wang YP. Transgenic Common Carp Do Not Have the Ability to Expand Populations. PLoS ONE, 2013, 8(6): e65506. 2. Du FK, Su JG, Huang R, Liao LJ, Zhu ZY, Wang YP. Cloning and preliminary functional studies of the JAM-A gene in grass carp (Ctenopharyngodon idellus). Fish & Shellfish Immunology, 2013, 34: 1476-1484. 3. Huang R, Lv JJ, Luo DJ, Liao LJ, Zhu ZY, Wang YP. Identification, characterization and the interaction of Tollip and IRAK-1 in grass carp (Ctenopharyngodon idellus). Fish & Shellfish Immunology, 2012, 33(3): 459-467. 4. Huang R, Dong F, Jang SH, Liao LJ, Zhu ZY, Wang YP. Isolation and analysis of a novel grass carp toll-like receptor 4 (tlr4) gene cluster involved in the response to grass carp reovirus. Developmental & Comparative Immunology, 2012, 38(2): 383-388. 5. Chen J, Li C, Huang R, Du FK, Liao LJ, Zhu ZY, Wang YP. Transcriptome analysis of head kidney in grass carp and discovery of immune-related genes. BMC Veterinary Research, 2012, 8: 108. 6. Lv JJ, Huang R, Li HY, Luo DJ, Liao LJ, Zhu ZY, Wang YP. Cloning and characterization of the grass carp (Ctenopharyngodon idella) Toll-like receptor 22 gene, a fish-specific gene. Fish & Shellfish Immunology, 2012, 32(6): 1022-1031. 7. Jang SH, Liu H, Su JG, Dong F, Xiong F, Liao LJ, Wang YP, Zhu ZY. Construction and Characterization of Two Bacterial Artificial Chromosome Libraries of Grass Carp. Marine Biotechnology, 2010, 12: 261-266. 8. Zhong S, Wang YP, Chen Z, Lu P, Liao LJ, Zhu ZY. Shortening the breeding period of transgenic fish using growth hormone levels as an indicator. Journal of Applied Ichthyology, 2010, 26: 904-907. 9. Zhong S, Wang YP, Pei DS, Luo DJ, Liao LJ, Zhu ZY. A one-year investigation of the relationship between serum GH levels and the growth of F4 transgenicand non-transgenic common carp Cyprinus carpio. Journal of Fish Biology, 2009, 75: 1092-1100. 10. Su JG, Zhu ZY, Wang YP, Jang SH. Isolation and characterization of Argonaute 2: a key gene of the RNA interference pathway in the rare minnow, Gobiocypris rarus. Fish & Shellfish Immunology, 2009, 26(1): 164-170. 11. Su JG, Yang C, Zhu ZY, Wang YP, Jang SH, Liao LJ. Enhanced grass carp reovirus resistance of Mx-transgenic rare minnow (Gobiocypris rarus). Fish & Shellfish Immunology, 2009, 26(6): 828-835. 12. Chen CL, Sun XY, Liao LJ, Luo SX, Li ZQ, Zhang XH, Wang YP, Guo QL, Fang Q, Dai HP. Antigenic analysis of grass carp reovirus using single-chain variable fragment antibody against IgM from Ctenopharyngodon idella. Science China Life Sciences. 2013, 56(1) 59-65. 13. Zhong CR, Song YL, Wang YP, Li YM, Liao LJ, Xie SQ, Zhu ZY, Hu W. Growth hormone transgene effects on growth performance are inconsistent among offspring derived from different homozygous transgenic common carp (Cyprinus carpio L.). Aquaculture, 2012, 356-357: 404-411. 14. Guan B, Ma H, Wang YP, Hu YL,Lin ZP, Zhu ZY, Hu W. Vitreoscilla Hemoglobin (VHb) Overexpression Increases Hypoxia Tolerance in Zebrafish (Danio rerio).Marine Biotechnology, 2011, 13: 336-344. 15. Xiao FS. Wang YP, Yan W, Chang MX, Yao WJ, Xu QQ, Wang XX, Gao Q, Nie P. Ig heavy chain genes and their locus in grass carp Ctenopharyngodon idella. Fish & Shellfish Immunology, 2010, 29: 594-599. 16. Huang R, Zhong S, Liu H, Wang YP, Hu W, Guo QL. Identification and characterization of common carp (Cyprinus carpio L.) granzyme A/K, a cytotoxic cell granule-associated serine protease. Fish & Shellfish Immunology, 2010, 29(3): 388-398. 17. Duan M, Zhang TL, Hu W, Guan B, Wang YP, Li ZJ, Zhu ZY. Increased mortality of growth-enhanced transgenic common carp (Cyprinus carpio L.) under short-term predation risk. Journal of Applied Ichthyology, 2010, 26 : 908-912. 18. Zhang LL,Luo Q, Fang Q, Wang YP. An improved RT-PCR assay for rapid and sensitive detection of grass carp reovirus. Journal of Virological Methods, 2010, 169: 28-33. 19. Huang R, Gao LY, Wang YP, Hu W, Guo QL. Structure, organization and expression of common carp (Cyprinus carpio L.) NKEF-B gene. Fish & Shellfish Immunology, 2009, 26(2): 220-229. 20. Huang R, Sun XF, Hu W, Wang YP, Guo QL. Structure, organization and expression of common carp (Cyprinus carpio L.) SLP-76 gene. Fish & Shellfish Immunology, 2008, 24(5): 530-541. 21. Su JG, Zhu ZY, Wang YP, Zou J, Hu W. Toll-like receptor 3 regulates Mx expression in rare minnow Gobiocypris rarus after viral infection. Immunogenetics, 2008, 60: 195-205. 22. Su JG, Zhu ZY, Xiong F, Wang YP. Hybrid Cytomegalovirus-U6 Promoter-based Plasmid Vectors Improve Efficiency of RNA Interference in Zebrafish. Marine Biotechnology, 2008, 10: 511-517. 23. Su JG, Zhu ZY, Wang YP, Xiong F, Zou J. The Cytomegalovirus Promoter-Driven Short Hairpin RNA Constructs Mediate Effective RNA Interference in Zebrafish In Vivo. Marine Biotechnology, 2008, 10: 262-269. 24. Su JG, Zhu ZY, Wang YP. Molecular cloning, characterization and expression analysis of the PKZ gene in rare minnow Gobiocypris rarus. Fish & Shellfish Immunology, 2008, 25(1-2): 106-113. 25. 连灏, 石米娟, 杜富宽, 江遥, 黄容, 廖兰杰, 汪亚平, 朱作言. 草鱼(AG)微卫星标记克隆及特征分析. 水生生物学报, 2012, 36(1): 29-34. 26. 李偲, 刘航, 黄容, 李华英, 石米娟, 廖兰杰, 朱作言, 汪亚平. 草鱼Ⅰ型微卫星标记的发掘及其多态性检测. 水生生物学报, 2011, 35(4): 681-687. 27. 廖莎, 陈芸, 杜富宽, 汪亚平, 廖兰杰, 朱作言. 抗草鱼出血病转基因稀有鮈鲫的初步研究. 水生生物学报, 2010, 34(4): 837-841. 28. 杨琳, 汪亚平, 廖兰杰, 朱作言. 小发夹RNA(shRNA)在稀有鮈鲫胚胎中的表达. 水生生物学报, 2010, 34(5): 1031-1036. 29. 钟山, 汪亚平, 陈竹, 管波, 廖兰杰, 朱作言. 饥饿条件下转基因鲤鱼生长激素变化特点研究. 水生生物学报, 2009, 33(6): 1046-1050. 30. 钟山, 罗大极, 吴刚, 徐靖, 汪亚平, 朱作言. 两种不同终止子在转基因鲤鱼中的促生长效应. 遗传, 2009, 31(8): 831-836. |